Staff Profile

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Miss Jana Stastna

Postdoctoral Research and Teaching Fellow

School: School of Human and Life Sciences

Campus: Canterbury

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Profile summary

I obtained my undergraduate degree in Biosciences (2013) at Canterbury Christ Church University (CCCU). I obtained my PhD in Biological Sciences at CCCU (2017).  

Research and knowledge exchange

I am interested in the natural variation in ageing and stress responses in Caenorhabditis elegans. Stress and lifespan are closely related, with many mutations that alter lifespan also affecting stress-response and nutrient sensing. Experiments on stress factors can therefore provide insight into the mechanisms of ageing.

The free living round worm Caenorhabditis elegans are one of the fastest, cheapest and most efficient ways to learn about ourselves. The nematode C. elegans has long become established as a standard experimental system for the investigation of great variety of biological processes: aging, sex determination, cell lineage, cell death, myogenesis and neural development and specification to name a few.

Most studies in C. elegans have been using one canonical strain, Bristol (N2) as a reference genotype. Therefore, what is needed is a closer look at the freshly derived-wild isolates in order to obtain a more realistic idea about the effects of dietary restriction and other stresses.

Teaching and subject expertise

Level 0 - Biological Concepts

Level 1 - Diversity of Life

Level 2 - Evolution

External activities

Stastna J.J., Snoek L.B., Riksen J.A.G., Vujakovic A., Schulenburg H., Kammenga J.E. & Harvey S.C.  (2016) Natural variation in stress response in the Nematode Caenorhabditis elegans using a novel multi-parent recombinant inbred line panel. Talk. BSRA Meeting, Dutham, 4th – 6th July

Stastna J.J., Snoek L.B., Riksen J.A.G., Vujakovic A., Schulenburg H., Kammenga J.E. & Harvey S.C.  (2016) Natural Variation in Acute stress resistance, DR and lifespan in a multi-parent recombinant inbred line panel in C. elegans. Poster presentation. European Worm Meeting, Berlin, 1st – 4th June     

Stastna J.J., Snoek L.B., Volkers R.J.M., Riksen J.A.G., Vujakovic A., Schulenburg H., Kammenga J.E. & Harvey S.C.  (2015) Acute stress resistance, DR and lifespan in a multi-parent recombinant inbred line panel. Poster presentation. C. elegans International meeting, UCLA, Los Angeles 24th – 28th June

Stastna J.J., Snoek L.B., Kammenga J.E. & Harvey S.C. (2015) Dietary restriction is not a universal means of prolonging the lifespan in nematode Caenorhabditis elegans. Poster presentation. Healthy Ageing: From Molecules to Organisms, Cambridge, 18th – 20th May

Stastna J.J., Snoek L.B., Volkers R.J.M., Riksen J.A.G., Schulenburg H., Kammenga J.E. & Harvey S.C. (2014) Natural variation in lifespan and dietary restriction effects in a multi-parent recombinant inbred line panel in Caenorhabditis elegans. Poster presentation. Evolutionary Biology of Caenorhabditis and other Nematodes, Cambridge, 14th-17th June

Stastna J.J., Snoek, L.B., Volkers R.J.M., Riksen J.A.G., Kammenga J.E., Harvey S.C. (2014) Lifespan and the effects of dietary restriction in a multi-parent recombinant inbred line panel in Caenorhabditis elegans. Poster presentation. European C. elegans Meeting, Berlin, 15th – 17th May

Publications and research outputs

Stastna J.J ., Snoek L.B., Kammenga J.E. & Harvey S.C. (2015) Genotype-dependent lifespan effects in peptone deprived Caenorhabditis elegans. Scientific reports , 5:16259. DOI:10.1038/srep16259 http:// www.nature.com/articles/srep16259

Green J.W.M., Stastna J.J ., Orbidans H.E. & Harvey S.C. (2014) Highly polygenic variation in environmental perception determines dauer larvae formation in growing populations of  Caenorhabditis elegans  PLoS One , 9(11):e112830. doi:10.1371/journal.pone.0112830  http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112830

Snoek L.B., Orbidans H.E., Stastna J.J., Aartse A., Rodriguez M., Riksen J.A.G., Kammenga J.E. & Harvey S.C. (2014) Widespread genomic incompatibilities inCaenorhabditis elegans .  G3 (Bethesda),  4:1813-1823.http://www.g3journal.org/content/4/10/1813.abstract 

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Last edited: 05/12/2017 03:57:00