Dr Fang Xiao

I joined CCCU in 2021 and I am now the Course Advocate for Biomedical Science.

My research areas are immune regulation in transplantation and human liver disease.

I was qualified as a clinician in China and started my scientific pathway after obtaining PhD from Queen Mary University London in the UK. After a brief spell at University College London, I moved to King’s College London working with Profs Robert Lechler and Giovanna Lombardi. There I used humanized mice as a model for the study of human immune rejection of allografts.  As such, I was awarded an MRC project grant to further develop my research.   

I am currently an Honorary Research Fellow in the Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, and an Adjunct Professor of the Second Affiliated Hospital of Xi’an Jiao Tong University, China. 

I teach on modules from level 4 to level 6 for Life Science programmes.

I am a Fellow of the Higher Education Academy and the Programme Advocate for the Biomedical Science BSc.

Current research interests

My research interests are on the regulatory properties of immune cells in transplantation and disease settings such as liver injury and diabetes. I am investigating the role of tolerogenic dendritic cells in controlling immune responses with the outlook to exploring their therapeutic potentials.

Research funding

Preclinical in vivo assessment of a combination of protein and cell therapies to prevent human islet transplant rejection as a cure for Type 1 diabetes MRC Medical Research Council Lombardi, G., Dorling, A., Huang, G., Lechler, R., Xiao, F.

£370,094.00

1/01/2013 → 31/12/2015

The role of C5a receptor signaling in the function of regulatory T cells: A possible therapeutic target for tolerance induction in transplantation

King’s College London

Xiao, F., Lombardi, G.

£1,900

01/01/2013→ 30/06/2013

Research projects

· The role of transcription factor T-bet in the maintenance of phenotype of adipose tissue-resident regulatory T cells (past)

· Novel therapeutic strategies to promote tolerance to pancreatic islet allograft (past)

· Protein disulphide isomerase located on the cell surface of platelets and vascular wall cells (past)

· Exploring natriuretic peptide receptor-C agonist (past)

· The vascular renin-angiotensin-aldosterone system (past)

· The exploration of drugs inhibitory to the vascular remodelling (past)