Revolutionary new method to map animal genomes developed
10 January 2017
Researchers from the School of Human and Life Sciences at Canterbury Christ Church University have been involved in a new study to develop a new cost effective approach to mapping and assembling genome.
The research, led by the Royal Veterinary College (RVC) and the University of Kent, and funded by the Biological Sciences Research Council (BBSRC), developed the approach using a novel method that is particularly effective for bird species.
Senior Lecturer in the School of Human and Life Sciences, Dr Katie Fowler’s and her PhD student, Anjali Mandawala, were also part of the research project. Dr Fowler’s research at Christ Church focusses on non-human embryology, specifically embryo freezing and the application of time lapse embryo imaging. She is currently working on an industry-led project in this research area, in collaboration with Genea Biomedx an in vitro fertilisation (IVF) company at Discovery Park.
Dr Fowler said: “Anjali and I were very excited to be a part of the research in conjunction with the Royal Veterinary College and the University of Kent and we hope to maintain these ongoing collaborations in the future.
This research describes a new, quick and practical approach to improve genome assemblies, which are usually highly fragmented, by upgrading these to larger, chromosome sized sequences. This is important to improve our understanding of genome evolution and can be applied to many species.”
The research paper: Upgrading short read animal genome assemblies to chromosome level using comparative genomics and a universal probe set, has been published in the academic journal Genome Research.